Research from Charles Carter's laboratory

Protein crystallography; aminoacyl-tRNA synthetases, nucleoside deaminases, experimental design, statistical direct methods and the phase problem

Research Areas:



(1) Cytidine deaminase: Structural studies of the reaction profile.



(2) Tryptophanyl-tRNA synthetase; conformational coupling in catalysis and recognition.



(3) Solving macromolecular structures using Bricogne's Bayesian paradigm.



(4) Stationary points, reproducibility, and multidimensional sampling of response surfaces for crystal growth