C.W.Carter, Jr. Home Page

Laboratory of Charlie Carter

  • Visitors:
  • Postdocs and Students:

  • Technical support:
  • Biochemistry 655 Syllabus

    Biochemistry 655 Final Examination

    Final_655_07.kin

    folds.kin

    Course Evaluation form

    Biochemistry 134 examples

    open_openW.tif

    C_White.pdf

    BILLARDETDOMINO

    67_M-B.xls

    MC_ms.pdf

    Recent Highlights

    Retailleau, Pascal, Weinreb, Violetta, Hu, Mei, and Carter, Charles W. Jr., (2007) Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Adenosine-5'Tetraphosphate: Evidence for Distributed Use of Catalytioc Binding Energy in Amino Acid Activation by Class I Aminoacyl-tRNA Synthetases; J. Mol. Biol. 369:108-128. 60:66-81.pdf

    Pham, Yen, Li, Li, Kim, Aram, Erdogan, Ozgun, Weinreb, Violetta, Butterfoss, Glenn L. Kuhlman, Brian, and Carter, Charles W. Jr., (2007) A Minimal TrpRS Catalytic Domain Supports Sense/Antisense Ancestry of Class I and II Aminoacyl-tRNA Synthetases 60:66-81.pdf

    Kapustina, Maryna, Hermans, Jan, and Carter, Charles W. Jr., (2006) Potential of Mean Force Estimation of the Relative Magnitude of the Effect of Errors in Molecular Mechanics Approximations; J. Mol. Biol. 362:1117-1180. 60:66-81.pdf

    Kapustina, Maryna and Carter, Charles W. Jr., (2005) Computational Studies of Tryptophanyl-tRNA Synthetase: Activation of ATP by Induced-Fit, J. Mol. Biol. 362, 1159-1180, 60:66-81.pdf

    Carter, Charles W. Jr. & Ries-Kautt, M., (2006) Improving Marginal Crystals 60:66-81.pdf

    Roach, Jeffrey, Sharma, Shantanu, Kapustina, Maryna, and Carter, Charles W. Jr., (2005) structure Alignment via Delaunay Tetrahedralization; Proteins: Structure, Function, and Bioinformatics, 60:66-81.pdf

    Biochemistry 655 Midterm Examination

    07Midterm.kin

    folds.kin

    Course Evaluation form

    Biochemistry 134 examples

    open_openW.tif

    C_White.pdf

    MC_ms.pdf

    Recent Highlights

    Retailleau, Pascal, Weinreb, Violetta, Hu, Mei, and Carter, Charles W. Jr., (2007) Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Adenosine-5'Tetraphosphate: Evidence for Distributed Use of Catalytioc Binding Energy in Amino Acid Activation by Class I Aminoacyl-tRNA Synthetases; J. Mol. Biol. 369:108-128. 60:66-81.pdf

    Pham, Yen, Li, Li, Kim, Aram, Erdogan, Ozgun, Weinreb, Violetta, Butterfoss, Glenn L. Kuhlman, Brian, and Carter, Charles W. Jr., (2007) A Minimal TrpRS Catalytic Domain Supports Sense/Antisense Ancestry of Class I and II Aminoacyl-tRNA Synthetases 60:66-81.pdf

    Kapustina, Maryna, Hermans, Jan, and Carter, Charles W. Jr., (2006) Potential of Mean Force Estimation of the Relative Magnitude of the Effect of Errors in Molecular Mechanics Approximations; J. Mol. Biol. 362:1117-1180. 60:66-81.pdf

    Kapustina, Maryna and Carter, Charles W. Jr., (2005) Computational Studies of Tryptophanyl-tRNA Synthetase: Activation of ATP by Induced-Fit, J. Mol. Biol. 362, 1159-1180, 60:66-81.pdf

    Carter, Charles W. Jr. & Ries-Kautt, M., (2006) Improving Marginal Crystals 60:66-81.pdf

    Roach, Jeffrey, Sharma, Shantanu, Kapustina, Maryna, and Carter, Charles W. Jr., (2005) structure Alignment via Delaunay Tetrahedralization; Proteins: Structure, Function, and Bioinformatics, 60:66-81.pdf

    Chester, Ann, Weinreb, V., Carter, C.W., Jr., and Navaratnam, N. (2004) “Optimization of apolipoprotein B mRNA editing by APOBEC1 apoenzyme and the role of its auxiliary factor, ACf ” RNA, 10:1399-1411.pdf

    Carter, C. W., Jr. (2005) “Tryptophanyl-tRNA Synthetases; in The Aminoacyl-tRNA Synthetases, ed by M. Ibba, C. Francklyn, S. Cusack, Landes Biosciences, Chapter 12:99-110. 10:705-708.pdf

    Pendergraft, W. F., Preston, G.A., Shah, R., Tropsha, A., Carter, C.W., Jr, Jennette, J.C., and Falk, R.J. (2003) “Autoimmunity is triggered by cPR-3 (105-201), a protein complementary to human autoantigen proteinase-3; Nature Medicine, 10:72-79 pdf

    Roach, J. M., and Carter, Charles W., Jr. (2003) “Local squaring functions for non-spherical templates” Acta Crystallographica Section A , 10:A59:273-280.pdf

    Retailleau, P., Huang, X. Yin, Y., Hu, M., Weinreb, V., Vachette, P., Vonrhein, C., Bricogne, G., Roversi, P., Ilyin, V., and Carter, C. W. Jr. (2003) Interconversion of ATP binding and conformational free energies by Tryptophanyl-tRNA Synthetase: structures of ATP bound to open and closed, pre-transition-state conformations”, J. Mol. Biol., 325:39-63 pdf

    Carter, C. W., Jr., and Duax, William L. (2002) “Did tRNA Synthetase Classes Arise on Opposite Strands of the Same Gene?” Molecular Cell, 10:705-708.pdf

    Carter, C. W., Jr., LeFebvre, B., Cammer, S. A., Tropsha, A. & Edgell, M. H. (2001). Four-body potentials reveal protein-specific correlations to stability changes caused by hydrophobic core mutations. Journal of Molecular Biology 311(4):625-638.pdf

    Carter, Charles W., Jr., Tropsha, Alex, and Edgell, Marshall. (2002) “Energetics of Enzyme Stability”, Trends in Biotechnology, 20:2-3.pdf

    Retailleau, P., Yin, Y., Hu, M., Roach, J. M., Bricogne, G., Vonrhein, C., Roversi, P., Blanc, E., Sweet, R. M., and Carter, C. W., Jr , (2001) “High Resolution Experimental Phases for Tryptophanyl-tRNA (TrpRS) Synthetase Complexed with Tryptophanyl-5’AMP”, Acta Crystallographica, D57, 1595-1608.pdf

    Navaratnam, N., Fujino, T., Bayliss, J., Jarmuz, A., How, A., Richardson, N., Angelika, S., Battacharya, S., Carter, C. W., Jr. & Scott, J. (1998) E. coli Cytidine Deaminase Provides Molecular Model for ApoB RNA Editing: Implications for Asymmetric RNA Substrate Presentation and Evolution of C to U Editing. J. Mol. Biol. 275:695-714 pdf

    A few tangential matters of interest to me



    Activities:

    Using Bricogne's Bayesian
    © 9. Jan. 1996 by C. W. Carter, Jr. carter@med.unc.edu