Laboratory of Charlie Carter
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Vita
- Address:
Department of Biochemistry and Biophysics
University of North Carolina
323A Mary Ellen Jones Building - Phone: (919) 966-3263
- FAX: (919) 966-2852
- Email: carter@med.unc.edu
Research Interests
Laboratory of Charlie Carter | ||
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Weinreb, Violetta, Li, Li, Campbell, Cassandra l., Kaguni, Laurie S. and Carter, Charles W. Jr., (2009) Mg2+-Assisted Catalysis by B. stearothermophilus TrpRS Is Promoted by Allosteric Effects. Structure 17:952-964. 60:66-81.pdf
Laowanapiban, Poramaet, Kapustina, Maryna, Vonrhein, Clemens, Delarue, Marc, Koehl, Patrice, and Charlies W. Carter, Jr. (2009) Independent saturation of three TrpRS subsites generates a partially assembled state similar to those observed in molecular simulations; Proc. Nat. Acad. Sci. USA. 106:1790-1795. 60:66-81.pdf
Weinreb, Violetta, and Carter, Charles W. Jr., (2008) Mg2+-Free Bacillus stearothermophilus Tryptophanyl-tRNA Synthetase Retains a Major Fraction of the Overall Rate Enhancement for Tryptophan Activation; J. Am. Chem. Soc. 130:1488-1494. 60:66-81.pdf
Kapustina, Maryna, Weinreb, Violetta, Li, Li, Kuhlman, Brian, and Charlies W. Carter, Jr. (2007) A Conformational Transition State Accompanies Tryptophan Activation by B. stearothermophilus Tryptophanyl-tRNA Synthetasear simulations; Structure 15:1272-1284. 60:66-81.pdf
Carter, Charles W. Jr., (2008) Whence the Genetic Code? Thawing the Frozen Accident; Nature Heredity 369:108-128. 60:66-81.pdf
Retailleau, Pascal, Weinreb, Violetta, Hu, Mei, and Carter, Charles W. Jr., (2007) Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Adenosine-5'Tetraphosphate: Evidence for Distributed Use of Catalytioc Binding Energy in Amino Acid Activation by Class I Aminoacyl-tRNA Synthetases; J. Mol. Biol. 369:108-128. 60:66-81.pdf
Pham, Yen, Li, Li, Kim, Aram, Erdogan, Ozgun, Weinreb, Violetta, Butterfoss, Glenn L. Kuhlman, Brian, and Carter, Charles W. Jr., (2007) A Minimal TrpRS Catalytic Domain Supports Sense/Antisense Ancestry of Class I and II Aminoacyl-tRNA Synthetases 60:66-81.pdf
Kapustina, Maryna, Hermans, Jan, and Carter, Charles W. Jr., (2006) Potential of Mean Force Estimation of the Relative Magnitude of the Effect of Errors in Molecular Mechanics Approximations; J. Mol. Biol. 362:1117-1180. 60:66-81.pdf
Kapustina, Maryna and Carter, Charles W. Jr., (2005) Computational Studies of Tryptophanyl-tRNA Synthetase: Activation of ATP by Induced-Fit, J. Mol. Biol. 362, 1159-1180, 60:66-81.pdf
Carter, Charles W. Jr. & Ries-Kautt, M., (2006) Improving Marginal Crystals 60:66-81.pdf
Roach, Jeffrey, Sharma, Shantanu, Kapustina, Maryna, and Carter, Charles W. Jr., (2005) structure Alignment via Delaunay Tetrahedralization; Proteins: Structure, Function, and Bioinformatics, 60:66-81.pdf
Retailleau, Pascal, Weinreb, Violetta, Hu, Mei, and Carter, Charles W. Jr., (2007) Crystal Structure of Tryptophanyl-tRNA Synthetase Complexed with Adenosine-5'Tetraphosphate: Evidence for Distributed Use of Catalytioc Binding Energy in Amino Acid Activation by Class I Aminoacyl-tRNA Synthetases; J. Mol. Biol. 369:108-128. 60:66-81.pdf
Pham, Yen, Li, Li, Kim, Aram, Erdogan, Ozgun, Weinreb, Violetta, Butterfoss, Glenn L. Kuhlman, Brian, and Carter, Charles W. Jr., (2007) A Minimal TrpRS Catalytic Domain Supports Sense/Antisense Ancestry of Class I and II Aminoacyl-tRNA Synthetases 60:66-81.pdf
Kapustina, Maryna, Hermans, Jan, and Carter, Charles W. Jr., (2006) Potential of Mean Force Estimation of the Relative Magnitude of the Effect of Errors in Molecular Mechanics Approximations; J. Mol. Biol. 362:1117-1180. 60:66-81.pdf
Kapustina, Maryna and Carter, Charles W. Jr., (2005) Computational Studies of Tryptophanyl-tRNA Synthetase: Activation of ATP by Induced-Fit, J. Mol. Biol. 362, 1159-1180, 60:66-81.pdf
Carter, Charles W. Jr. & Ries-Kautt, M., (2006) Improving Marginal Crystals 60:66-81.pdf
Roach, Jeffrey, Sharma, Shantanu, Kapustina, Maryna, and Carter, Charles W. Jr., (2005) structure Alignment via Delaunay Tetrahedralization; Proteins: Structure, Function, and Bioinformatics, 60:66-81.pdf
Chester, Ann, Weinreb, V., Carter, C.W., Jr., and Navaratnam, N. (2004) “Optimization of apolipoprotein B mRNA editing by APOBEC1 apoenzyme and the role of its auxiliary factor, ACf ” RNA, 10:1399-1411.pdf
Carter, C. W., Jr. (2005) “Tryptophanyl-tRNA Synthetases; in The Aminoacyl-tRNA Synthetases, ed by M. Ibba, C. Francklyn, S. Cusack, Landes Biosciences, Chapter 12:99-110. 10:705-708.pdf
Pendergraft, W. F., Preston, G.A., Shah, R., Tropsha, A., Carter, C.W., Jr, Jennette, J.C., and Falk, R.J. (2003) “Autoimmunity is triggered by cPR-3 (105-201), a protein complementary to human autoantigen proteinase-3; Nature Medicine, 10:72-79 pdf
Roach, J. M., and Carter, Charles W., Jr. (2003) “Local squaring functions for non-spherical templates” Acta Crystallographica Section A , 10:A59:273-280.pdf
Retailleau, P., Huang, X. Yin, Y., Hu, M., Weinreb, V., Vachette, P., Vonrhein, C., Bricogne, G., Roversi, P., Ilyin, V., and Carter, C. W. Jr. (2003) Interconversion of ATP binding and conformational free energies by Tryptophanyl-tRNA Synthetase: structures of ATP bound to open and closed, pre-transition-state conformations”, J. Mol. Biol., 325:39-63 pdf
Carter, C. W., Jr., and Duax, William L. (2002) “Did tRNA Synthetase Classes Arise on Opposite Strands of the Same Gene?” Molecular Cell, 10:705-708.pdf
Carter, C. W., Jr., LeFebvre, B., Cammer, S. A., Tropsha, A. & Edgell, M. H. (2001). Four-body potentials reveal protein-specific correlations to stability changes caused by hydrophobic core mutations. Journal of Molecular Biology 311(4):625-638.pdf
Carter, Charles W., Jr., Tropsha, Alex, and Edgell, Marshall. (2002) “Energetics of Enzyme Stability”, Trends in Biotechnology, 20:2-3.pdf
Retailleau, P., Yin, Y., Hu, M., Roach, J. M., Bricogne, G., Vonrhein, C., Roversi, P., Blanc, E., Sweet, R. M., and Carter, C. W., Jr , (2001) “High Resolution Experimental Phases for Tryptophanyl-tRNA (TrpRS) Synthetase Complexed with Tryptophanyl-5’AMP”, Acta Crystallographica, D57, 1595-1608.pdf
Navaratnam, N., Fujino, T., Bayliss, J., Jarmuz, A., How, A., Richardson, N., Angelika, S., Battacharya, S., Carter, C. W., Jr. & Scott, J. (1998) E. coli Cytidine Deaminase Provides Molecular Model for ApoB RNA Editing: Implications for Asymmetric RNA Substrate Presentation and Evolution of C to U Editing. J. Mol. Biol. 275:695-714 pdf
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Using Bricogne's Bayesian
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